All::Endocrinology::Diseases::Kallmann's syndrome

Intro

What causes Kallmann's syndrome?

  • hypogonadotropic hypogonadism
  • failure of GnRH-secreting neurons to migrate to the hypothalamus

How does Kallmann's syndrome typically present?

delayed puberty and anosmia

What hormone levels are found in Kallmann's syndrome?

LH, FSH levels are inappropriately low/normal

Whats the management of Kallmann's syndrome?

testosterone supplementation

What can be used in Kallmann's syndrome to help with fertility?

gonadotrophin supplementation may result in sperm production if fertility is desired later in life