All::Nephrology::Diseases::Acute interstitial nephritis

Study All (11) Add to study queue (11)

Intro

Study Intro (11) Add to study queue (11)

Acute interstitial nephritis accounts for {{c1::25%}} of drug-induced acute kidney injury

Acute interstitial nephritis

What are the drug causes of Acute interstitial nephritis?

  • penicillin
  • rifampicin
  • NSAIDs
  • allopurinol
  • furosemide

Acute interstitial nephritis

What are the systemic disease causes of Acute interstitial nephritis?

  • SLE
  • sarcoidosis
  • Sjögren's syndrome

Acute interstitial nephritis

What are the infective causes of Acute interstitial nephritis?

Hanta virus , staphylococci

Acute interstitial nephritis

What is the histological findings in Acute interstitial nephritis?

marked interstitial oedema and interstitial infiltrate in the connective tissue between renal tubules

Acute interstitial nephritis

What symptoms might Acute interstitial nephritis present with?

fever, rash, arthralgia

Acute interstitial nephritis

What changes are seen on bloods with Acute interstitial nephritis?

  • eosinophilia
  • mild renal impairment

Acute interstitial nephritis

What changes are seen in urine with Acute interstitial nephritis?

  • sterile pyuria
  • white cell casts

Acute interstitial nephritis

What is Acute interstitial nephritis?

is acute inflammation of the renal tubulo-interstitium

Acute interstitial nephritis

What is the treatment for Acute interstitial nephritis?

May resolve once the triggering medication is discontinued. Corticosteroid therapy may be associated with greater recovery of kidney function.

Acute interstitial nephritis

What are the lasting side effects from Acute interstitial nephritis?

Most patients have some residual renal impairment after an episode of acute interstitial nephritis.

Acute interstitial nephritis