All::Gastroenterology::Pharmacology::Hyoscine Butylbromide

Intro

What is the method of action of Hyoscine Butylbromide?

competitive inhibitor of acetylcholine which leads to:

  • increase heart rate and conduction
  • reduce smooth muscle tone and peristaltic contraction
  • reduce secretions

What is the main clinical use of Hyoscine Butylbromide?

  • reducing copious respiratory secretions at end of life
  • symptomatic relief for irritable bowel syndrome

What are the main adverse effects of Hyoscine Butylbromide?

  • tachycardia
  • dry mouth
  • constipation
  • urinary retention in patients with BPH

What are the main contraindications of Hyoscine Butylbromide?

  • angle-closure glaucoma
  • patients with arrhythmias