All::Respiratory::Pharmacology::Antimuscarinics

Intro

What is the method of action of Antimuscarinics?

  • Bind to the muscarinic receptor, where they act as a competitive inhibitor of acetylcholine
  • Leading to reduce smooth muscle tone and reduce secretions

What is the main clinical use of Antimuscarinics?

  • chronic obstructive pulmonary disease
  • asthma

What are the main adverse effects of Antimuscarinics?

dry mouth

What are the main contraindications of Antimuscarinics?

angle-closure glaucoma

What is a short acting Antimuscarinic?

ipratropium

What is a long acting Antimuscarinic?

tiotropium, glycopyrronium