What is Dabigatran?

an oral anticoagulant that works by being a direct thrombin inhibitor

What is the method of action of Dabigatran?

direct thrombin inhibitor

What are the specific indications of Dabigatran?

• an option in the prophylaxis of venous thromboembolism following hip or knee replacement surgery.
• prevention of stroke in patients with non-valvular atrial fibrillation who have one or more of the following risk factors present
  • previous stroke, transient ischaemic attack or systemic embolism
  • left ventricular ejection fraction below 40%
  • symptomatic heart failure of New York Heart Association (NYHA) class 2 or above
  • age 75 years or older
  • age 65 years or older with one of the following: diabetes mellitus, coronary artery disease or hypertension

What is the reversal agent for Dabigatran?

Idarucizumab