What is the method of action of Acetylcysteine?

Acetylcysteine serves as a prodrug to L-cysteine, a precursor to the biologic antioxidant glutathione. Glutathione is essential in the metabolism of NAPQI (toxic paracetamol metabolite)

What is the main clinical use of Acetylcysteine?

• Paracetamol overdose
• Reducing respiratory secretions

What are the main adverse effects of Acetylcysteine?

Risk of a non-immunoglobulin (Ig) E-mediated systemic hypersensitivity (anaphylactic) reaction when given IV in large doses