What is the method of action of Retinoids?

severe acne

What are the main adverse effects of Retinoids?

• teratogenicity
• dry skin, eyes and lips/mouth (most common side-effect)
• low mood
• raised triglycerides
• hair thinning
• nose bleeds (caused by dryness of the nasal mucosa)
• intracranial hypertension: isotretinoin treatment should not be combined with tetracyclines for this reason
• photosensitivity

How many patients go into long-term remission following taking Retinoids for severe acne?

Two-thirds

What drug class is Isotretinoin?

Retinoid