What is the drug class of Clozapine?

atypical antipsycotic

What patient groups is Clozapine used in?

only be used in patients resistant to other antipsychotic medication

What is the most significant effects of Clozapine?

significant risk of agranulocytosis

What are the Adverse effects of clozapine?

• agranulocytosis (1%), neutropaenia (3%)
• reduced seizure threshold - can induce seizures in up to 3% of patients
• constipation
• myocarditis: a baseline ECG should be taken before starting treatment-
• hypersalivation