What is Myxoedema coma?

an extreme or decompensated form of hypothyroidism

What are the main clinical features of Myxoedema coma?

• stupor
• hypothermia
• respiratory failure
• confusion
• coma

What are the TFT investigations findings in Myxoedema coma?

• TSH: markedly elevated in 95% of cases, 5% are caused by central TSH failure
• low free T4
• low T3

What is the management of Myxoedema coma?

• IV thyroid replacement
• IV fluid
• IV corticosteroids (until the possibility of coexisting adrenal insufficiency has been excluded)
• electrolyte imbalance correction
• sometimes rewarming

What is the prognosis of Myxoedema coma?

high mortality