What is Dermatitis herpetiformis?

an autoimmune blistering skin disorder associated with coeliac disease

What are the main clinical features of Dermatitis herpetiformis?

itchy, vesicular skin lesions on the extensor surfaces

What are the skin biopsy findings in Dermatitis herpetiformis?

direct immunofluorescence shows deposition of IgA in a granular pattern in the upper dermis

What is the management of Dermatitis herpetiformis?

• gluten-free diet
• dapsone

What is the pathophysiology of Dermatitis herpetiformis?

caused by deposition of IgA in the dermis

What are the main associations of Dermatitis herpetiformis?

coeliac disease