All::Neurology::Diseases::Creutzfeldt-Jakob disease
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What is Creutzfeldt-Jakob disease?
a rapidly progressive neurological condition caused by prion proteins
Creutzfeldt-Jakob diseaseWhat is the common presentation of Creutzfeldt-Jakob disease?
- dementia (rapid onset)
- myoclonus
What is seen in CSF in Creutzfeldt-Jakob disease?
usually normal
Creutzfeldt-Jakob diseaseWhat is seen in EEG in Creutzfeldt-Jakob disease?
biphasic, high amplitude sharp waves (only in sporadic CJD)
Creutzfeldt-Jakob diseaseWhat is seen in MRI in Creutzfeldt-Jakob disease?
hyperintense signals in the basal ganglia and thalamus
Creutzfeldt-Jakob diseaseWhat symptoms are seen in New variant CJD?
psychological symptoms such as anxiety, withdrawal and dysphonia are the most common presenting features
Creutzfeldt-Jakob diseaseWhat age is New variant CJD typically seen?
25 years
Creutzfeldt-Jakob diseaseWhat is the most common cause of Creutzfeldt-Jakob disease?
Sporadic CJD, caused by the spontaneous misfolding of prion-protein in an individual
Creutzfeldt-Jakob diseaseWhat age is Sporadic CJD typically seen?
65 years
Creutzfeldt-Jakob disease