All::Gastroenterology::Diseases::Eosinophilic oesophagitis
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What is the common presentation of Eosinophilic oesophagitis?
- In children, disease presents with failure to thrive due to food refusal
- Adults often experience dysphagia, strictures/ fibrosis (56%), food impaction (55%), regurgitation/ vomiting, anorexia
What patient groups is Eosinophilic oesophagitis most common?
- 3:1 male:female ratio
- Average age at diagnosis is 30-50 years old
What is the management of Eosinophilic oesophagitis?
- Dietary modification
- Topical steroids e.g. fluticasone and budesonide are options when dietary modification fails
- Oesophageal dilatation: 56% of patients require this at some point in their treatment to reduce the symptoms associated with oesophageal strictures
What are the main causes of Eosinophilic oesophagitis?
It is thought to be caused by an allergic reaction to ingested food
Eosinophilic oesophagitisWhat are the main risk factors of Eosinophilic oesophagitis?
- Allergies/ asthma: suffering from food/ environmental allergies or atopic dermatitis and asthma increases the risk of diagnosis
- Coexisting autoimmune disease e.g. coeliac disease
- Family history of eosinophilic oesophagitis or allergies
- Male sex
- Caucasian race
- Age between 30-50
What are the common complications of Eosinophilic oesophagitis?
- Strictures of the oesophagus (56%)
- Impaction: 55% of patients experience this, and 38% of these require endoscopic removal of the impaction
- Mallory-Weiss tears
What is Eosinophilic oesophagitis?
an allergic inflammation of the oesophagus causing pain and dysphagia
Eosinophilic oesophagitisHow is Eosinophilic oesophagitis diagnosed?
histological analysis of an oesophageal biopsy.
Eosinophilic oesophagitisWhat is the Prognosis of Eosinophilic oesophagitis?
It's a chronic condition which will return if treatment is stopped
Eosinophilic oesophagitis