All::Gastroenterology::Diseases::Eosinophilic oesophagitis

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What is the common presentation of Eosinophilic oesophagitis?

  • In children, disease presents with failure to thrive due to food refusal
  • Adults often experience dysphagia, strictures/ fibrosis (56%), food impaction (55%), regurgitation/ vomiting, anorexia

Eosinophilic oesophagitis

What patient groups is Eosinophilic oesophagitis most common?

  • 3:1 male:female ratio
  • Average age at diagnosis is 30-50 years old

Eosinophilic oesophagitis

What is the management of Eosinophilic oesophagitis?

  • Dietary modification
  • Topical steroids e.g. fluticasone and budesonide are options when dietary modification fails
  • Oesophageal dilatation: 56% of patients require this at some point in their treatment to reduce the symptoms associated with oesophageal strictures

Eosinophilic oesophagitis

What are the main causes of Eosinophilic oesophagitis?

It is thought to be caused by an allergic reaction to ingested food

Eosinophilic oesophagitis

What are the main risk factors of Eosinophilic oesophagitis?

  • Allergies/ asthma: suffering from food/ environmental allergies or atopic dermatitis and asthma increases the risk of diagnosis
  • Coexisting autoimmune disease e.g. coeliac disease
  • Family history of eosinophilic oesophagitis or allergies
  • Male sex
  • Caucasian race
  • Age between 30-50

Eosinophilic oesophagitis

What are the common complications of Eosinophilic oesophagitis?

  • Strictures of the oesophagus (56%)
  • Impaction: 55% of patients experience this, and 38% of these require endoscopic removal of the impaction
  • Mallory-Weiss tears

Eosinophilic oesophagitis

What is Eosinophilic oesophagitis?

an allergic inflammation of the oesophagus causing pain and dysphagia

Eosinophilic oesophagitis

How is Eosinophilic oesophagitis diagnosed?

histological analysis of an oesophageal biopsy.

Eosinophilic oesophagitis

What is the Prognosis of Eosinophilic oesophagitis?

It's a chronic condition which will return if treatment is stopped

Eosinophilic oesophagitis