All::Clinical Science::Study Design::Numbers needed to treat and absolute risk reduction

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What is meant by Numbers needed to treat?

a measure that indicates how many patients would require an intervention to reduce the expected number of outcomes by one

Numbers needed to treat and absolute risk reduction

How is Numbers needed to treat calculated?

1/(Absolute risk reduction)

Numbers needed to treat and absolute risk reduction

What is Experimental event rate (EER)?

(Number who had particular outcome with the intervention) / (Total number who had the intervention)

Numbers needed to treat and absolute risk reduction

What is Control event rate (CER)?

(Number who had a particular outcome with the control) / (Total number who had the control)

Numbers needed to treat and absolute risk reduction

How do you calculate Absolute risk reduction?

  • Experimental event rate - Control event rate
  • Control event rate -Experimental event rate

Depending on if the outcome is desirable or not

Numbers needed to treat and absolute risk reduction