All::Respiratory::Diseases::Kartagener's syndrome
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What are the main clinical features of Kartagener's syndrome?
- dextrocardia or complete situs inversus
- bronchiectasis
- recurrent sinusitis
- subfertility (secondary to diminished sperm motility and defective ciliary action in the fallopian tubes)
What is the pathophysiology of Kartagener's syndrome?
dynein arm defect results in immotile cilia
Kartagener's syndrome