All::Cardiovascular System::Pharmacology::Angiotensin II receptor blockers

Intro

When are Angiotensin II receptor blockers indicated?

Angiotensin II receptor blockers are generally used in situations where patients have not tolerated an ACE inhibitor, usually due to the development of a cough.

What are examples of Angiotensin II receptor blockers?

  • candesartan
  • losartan
  • irbesartan

Whats the MOA of Angiotensin II receptor blockers?

block effects of angiotensin II at the AT1 receptor

Evidence shows for Angiotensin II receptor blockers

  • they reduce progression of renal disease in patients with {{c1::diabetic nephropathy}}
  • that losartan reduces CVA and IHD mortality in {{c2::hypertensive patients}}