What is the inheritance pattern of Haemophilia?

X-linked recessive

What are the main clinical features of Haemophilia?

• haemoarthroses
• haematomas
• prolonged bleeding after surgery or trauma

What are the two types of Haemophilia?

• Haemophilia A (factor VIII)
• haemophilia B (Christmas disease) lack of factor IX

What is Haemophilia A a deficiency in?

factor VIII

What is Haemophilia B a deficiency in?

factor IX

What is seen on bloods tests for Haemophilia?

• prolonged APTT
• bleeding time, thrombin time, prothrombin time normal

What is a common complication of treatment of haemophilia A?

10-15% of patients develop antibodies to factor VIII treatment