All::Cardiovascular System::Diseases::Acute pericarditis
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Acute pericarditis is a condition referring to inflammation of the {{c1::pericardial sac}}
Acute pericarditisAetiology
What are the infective causes of Acute pericarditis?
- viral infections (Coxsackie)
- tuberculosis
Acute pericarditis post MI early (1-3 days): {{c1::fibrinous pericarditis}} late (weeks to months): {{c2::autoimmune pericarditis Dresslers syndrome}}
Acute pericarditisWhich connective tissue disease can cause Acute pericarditis?
- systemic lupus erythematosus
- rheumatoid arthritis
What malignancies can cause Acute pericarditis?
- lung cancer
- breast cancer
General
What are the features of Acute pericarditis?
- chest pain: may be pleuritic. Is often relieved by sitting forwards
- other symptoms include a non-productive cough, dyspnoea and flu-like symptoms
- pericardial rub
What ECG changes are seen in Acute pericarditis?
- the changes in pericarditis are often global/widespread, as opposed to the 'territories' seen in ischaemic events
- 'saddle-shaped' ST elevation
- PR depression: most specific ECG marker for pericarditis
all patients with suspected acute pericarditis should have {{c1::transthoracic echocardiography::?imaging}}
Acute pericarditisWhy is troponin checked in Acute pericarditis?
around 30% of patients may have an elevated troponin - this indicates possible myopericarditis
Acute pericarditisthe majority of patients with Acute pericarditis can be managed as {{c1::outpatients::IP/OP}}
Acute pericarditisWhats the treatment of Acute pericarditis?
- treat any underlying cause
- most patients however will have pericarditis secondary to viral infection, meaning no specific treatment is indicated
- a combination of NSAIDs and colchicine is now generally used for first-line for patients with acute idiopathic or viral pericarditis
- until symptom resolution and normalisation of inflammatory markers (usually 1-2 weeks) followed by tapering of dose recommended over