All::Gastroenterology::Pharmacology::Serotonin 5-HT3-receptor antagonists

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What an example of Serotonin 5-HT3-receptor antagonists?

Ondansetron

Serotonin 5-HT3-receptor antagonists

What is the method of action of Serotonin 5-HT3-receptor antagonists?

  • Blocking 5-HT3 receptors in the CTZ
  • Blocking 5-HT3 receptors in the gut (these are involved in responding to emetogenic stimuli)

Serotonin 5-HT3-receptor antagonists

What is the main clinical use of Serotonin 5-HT3-receptor antagonists?

Nausea and vomiting, particularly in the context of general anaesthesia and chemotherapy

Serotonin 5-HT3-receptor antagonists

What are the main contraindications of Serotonin 5-HT3-receptor antagonists?

Prolonged QT interval

Serotonin 5-HT3-receptor antagonists